EFEITOS ADVERSOS DOS BLOQUEADORES NEUROMUSCULARES E SEU USO DURANTE A COVID-19: UMA REVISÃO DE LITERATURA

Abstract

Neuromuscular blockers (NMB) are essential for patient intubation, as they act directly on muscle relaxation. These drugs had their use intensified during the Covid-19 pandemic, due to the high demand of people admitted to the Intensive Care Units (ICU) in a serious state of the disease. In this context, the research problem of this study was the following question: what is the impact of the adverse effects of the use of neuromuscular blockers (NMB) on the health of patients with Covid-19? Thus, the main objective is to understand the adverse effects of neuromuscular blockers, as well as contextualize their use in the Covid-19 pandemic; present the main symptoms and complications resulting from the Covid-19 infection; conceptualize neuromuscular blockers (NMB) and; to present the types of NMB, main characteristics and their effects. on the subject, published from 2020 to 2022. The results indicated that NMBs can be classified as depolarizing and non-depolarizing. Depolarizing NMBs have been associated with serious complications and contraindications in some studies, while non-depolarizing NMBs have characteristics such as fatigue, magnitude of response and low allergic reactions. It was also observed that these drugs are indispensable in intubation, even being replaced by sedatives in situations of shortage during the Covid-19 pandemic. Thus, it is concluded that despite the scope of adverse effects, the use of NMBs is essential in the intubation process, which requires health agencies to develop protocols and guidelines on their administration and adverse effects, instituting preventive measures and care for the patient. patient to minimize the impact of its use in the treatment of Covid-19.